Mpox vaccination

The vaccine against real smallpox also protects against diseases and severe courses of Mpox ("monkeypox"). It is intended for particularly vulnerable people - especially gay, bisexual and other men who have sex with changing partners.


The most important facts about monkeypox vaccination

  • The vaccine is usually well tolerated.
  • A previous smallpox vaccination also protects against Mpox ("monkeypox").
  • People with HIV can also be vaccinated.

What you should know about Mpox vaccination?

The smallpox vaccine Imvanex (Jynneos in the USA), which can also be used to protect against Mpox ("monkeypox"), is licensed in Europe for people aged 18 and over. The vaccine does not cause disease in humans and cannot replicate in human cells.

More than 10 percent of those vaccinated experience headaches, nausea, muscle pain and reactions at the injection site. However, the vaccination reactions usually subside after a few days. Already about two weeks after the first vaccination dose, the risk of contracting the disease is significantly reduced. For basic immunisation, a second vaccination dose should then be given at intervals of at least four weeks and no more than two years.

If you have already been vaccinated against real smallpox in the past, one vaccination dose is usually sufficient as a booster. According to current knowledge, having been infected with Mpox provides protection against further infection for several years, and vaccination is then not necessary.

Vaccination considerably reduces the risk of infection and a severe course of the disease, but does not offer 100% protection. The RKI's information on Mpox vaccination (also available in Arabic, English, French, Portuguese, Russian, Spanish and Turkish) contains all the important information on Mpox and vaccination. You can find it here.

Where to get vaccinated

Vaccination against Mpox is regulated differently in the individual federal states.

The following states give some information where you could get the vaccination:

Baden Württemberg

The following states give no information where you could get the vaccination:


If your state give no information where you could get the vaccination, we recommend that you obtain information from an AIDS help centre, a public health office or an HIV specialist practice in your area.



Monkeypox App:
Link to the monkeypox app of the Charité


[Translated with ]

Released by IWWIT Editorial Office
Last updated 15.11.2023

Related links/sources:


You can find testimonials on the topic of Mpox in our Blog.
Further information can be found on the website of the Deutschen Aidshilfe.